At a cellular level, those who consumed sucralose experienced increased glucose uptake, inflammation, and adipogenesis — all of which were most notable in people with obesity, according to Nabanita Kundu, PhD, of George Washington University (GWU) in Washington, D.C., and colleagues.
“We wanted to do a systematic study where we look at fat-derived stem cells and how these agents effect those looking at the gene expression and adipogenesis and inflammation, and also look at the human subjects’ fat who have actually taken these agents over a period of time,” explained senior study author
Source: Artificial Sweeteners Impact Metabolic Health Even on Cellular Level