The association between FTO SNPs and BMI and the risk of being overweight or obese has been confirmed in multiple populations [6,7,9–27]. The effect of FTO SNPs on BMI is modest, with those individuals homozygous for the risk allele weighing, on average, 3 kg more than those homozygous for the protective allele [7].
Source: The genetics of obesity: FTO leads the way
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